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brandy078 The benefit of isolating WhatsApp in its own user profile with is that WhatsApp will not be able to get the list of apps you have installed in any other profile. You also prevent WhatsApp from communicating with other Meta apps or embedded Meta libraries through IPC.
You could use a Private Space instead of a secondary user profile. It's a lot more convenient to use WhatsApp in a Private Space because a Private Space is essentially a secondary user profile but integrated in the Owner profile UI.