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And you see, this is mostly just debloated android.
GrapheneOS does a lot of things that should actually make it slower than AOSP (or less customized forks like LineageOS, iodeOS, CalyxOS, etc.) because it implements a lot of security mechanisms.
hardened_malloc is noticeably slower, even though it seems to be pretty optimized on GrapheneOS. On desktop Linux it slows down some things quite a lot.
Secure app spawning doesnt (?) use zygote to fork processes, so they share no (or less?) RAM content, but this increases RAM consumption.
Many apps are way more minimal though, but this depends on if you keep them. Still, also many FOSS alternative apps (Gallery, Filemanager) are way faster than the Google Apps. The preinstalled keyboard and camera are also really fast and small.
Nowadays you can roughly say: if an app is pretty small while having many features, it is well written.
Especially in the proprietary space, things are going crazy. It is pretty normal for random store, shopping, "social media" etc apps to be over 400MB! While these are mostly webapps.
Running webapps as much as possible is a very good idea. I have not tested, but assume Vanadium is also more easy on batterylife than Firefox mobile (Mull) or others.
You can also use the accessibility settings and disable animations, which may save a bit. On pixel phones, using a dark theme also helps a ton with energy consumption, due to the OLED display.