- Edited
I had reduced the number of profiles for a while due to an annoying fingerprint bug. Since the great workaround I've finally put some apps that I consider invasive (e.g. Google Maps) back into a separate profile - switching profiles is super smooth again.
For me personally, I don't see any usability advantage that iPhones would offer me - precisely not one for which I would want to sacrifice all the awesome security and privacy features a Pixel with GrapheneOS running on it offers (especially because you can easily regain nearly all the usability oft a non-customOS if you want - thanks to the one profile setup running sandboxed Google Play you mentioned above).
But that's finally a decision everyone has to make for themselves.