Thank you.
So I enabled Exploit Protection Compatibility Mode for this app, launched Lumafusion, doesnt work. Forced stop the app, lauched again the app, doesn't work.
I switched back to my main profile (Lumafusion is installed in another profile), then "Settings > Security > Disable Secure App Spawning", rebooted. Switched back to the other profile, launched Lumafusion, doesn't work.