To answer the OP, I have two Pixel phones (one for business and one for private use) and a Pixel Tablet (trying to replace my business laptop with it). Separation like this allows me to realize my threat model, as I don't use any Google Apps on the private phone, but I'm okay with Sandboxed Google Play on my business phone (for some proprietary apps to work) and even a bunch of Google Suite apps like Drive and Calendar on my Tablet since the company depends on these apps for collaboration.
So in case you struggle to solve your privacy balance with juggling profiles or apps on one device, using two or three devices might be the best solution, I know it is for me.