de0u EDS Lite is kind of like VeraCrypt - all files are stored in a single encrypted container. On the other hand, Cryptomator is storing each original file in its own encrypted file, this works well for the cloud but with USB drive storage could be a pro or con, depending on your workflow.
EDS Lite is no longer maintained which is significant downside, while Cryptomator is actively maintained.
There is a third option DroidFS which is kind of like Crypromator but implements gocryptfs approach.
In practice, they all are probably fine to use, try and see which one you like more.