Make a good thread model to identify the enemies first and pick your battles and arsenal wisely to avoid getting burned out over time.
Also: Avoid enemies (e.g. social media, big tech etc.) and don't make new/unnecessary ones.
There are so many ways to answer your question, but in the end the "correct" answer will be different for everyone. In my experience, most of the time the issue is a lacking threat model in the first place. People worry too much about the wrong things...