GHqBD_1942 Yes, a lot, from my experience. A single e-sim drains much less than dual setup. Without any sim at all, you should have even better battery life. My phone can withstand a full day of heavy use with 15-20% left at the end of the day or a couple of days with very light use. This is with 24/7 VPN usage.
If you're going to reinstall through a PC, I suggest you burn a clean copy of Linux Mint/Ubuntu to a USB and boot through that and do the manual install with adb/fastboot to be in full control of the process.