If all the apps are sandboxed, what is the privacy benefit to having different types of apps on different profiles?

I have found a few apps that require native code debugging be allowed. Will enabling this for one app reduce the effectiveness of the sandbox for all apps, just the one, or all and only apps in that user profile?

    Okayhello If all the apps are sandboxed, what is the privacy benefit to having different types of apps on different profiles?

    https://seprand.github.io/articles/best-user-profile-setup/

    Will enabling this for one app reduce the effectiveness of the sandbox for all apps, just the one, or all and only apps in that user profile?

    As long as you're changing the per-app setting, just the one app for that profile specifically.