Here is an example of the App SwissID which has Play Integrity enforced: https://nowtransfer.de/f9a5b2219083
I tried it on secondary profile with Google Services enabled but not logged in.
The German text translates (via deepl) into:
"Device appears to be insecure
The integrity algorithm of Google Play Integrity algorithm indicates that your device and/or operating system does not meet our security requirements.
We recommend that you run the SwissID app on another device.
If you believe that this is an error, please is a mistake, please contact customer service.
Please note Rooted Android devices and certain operating systems, e.g. GrapheneOS, do not pass the Google Play integration check."
So it is explicitly stated that GrapheneOS is blocked due to the Google Play Integrity algorithm.