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@Sindbad while the following won't help regarding GrapheneOS or Pixel devices, this is exactly what Daylight is doing with their flicker-free and no-blue light DC-1 tablet. Keep in mind, this is a health-oriented device designed for such people, but Daylight is taking on a hugely important topic and doing some seriously cool stuff with their display technology.
Seth for Privacy (GrapheneOS advocate) reviewed his unit here:
https://sethforprivacy.com/posts/daylight-dc1-magical-imperfection/
If anyone wants to nerd out further on this stuff, Dr. Jack Kruse is generally regarded as the go-to source for all things circadian biology and how it pertains to the technology we use.