RMghed There's nothing inherently unsafe about using a SIM card. It is also important to note that a SIM card is not needed to connect to cellular towers, and that a device can still connect to them without one being used.
This is how you can, for example, call emergency services without a SIM being required.
If you don't want to connect to cell towers, airplane mode is what you want to use, not just removing the SIM from the device.
More info here: https://grapheneos.org/faq#cellular-tracking