I am still trying to get everything configured to work exactly the way I want, but right now I have these;
Owner: I use this for calls and text messages (SMS) and some simple browsing not through VPN. Here I currently also have non-work related ssh keys.
Work: I use this for all work-related applications like email, ssh (with keys and scripts to do the basic stuff), wireguard for accessing internal work services like redmine, gitlab and so on. Also work chat applications like Telegram, KeyBase and WeChat. This helps me to log out of work while still allowing me to log back on with ease (I run a small IT company).
Entertainment: Here I have my private chat applications like Keybase and Telegram (different accounts than under Work), video/music/audiobook players, ... I have my normal email configured in this profile. Traffic goes through VPN for some added privacy.
Gulag: Here I have the digital gulag applications as required to live a life in northern Europe today; bankid (digital ID), swish (money transfer), bank apps, parking apps, taxi apps, google maps, and so on. I have not decided how to handle this in relation to VPN traffic. Some of the digital gulag applications already require and check location when doing money transfers for example. I am of the belief that this will get a lot worse in the future...
WorldGulag: Here I have the digital gulag applications as required when traveling or living abroad: hotels, flights, taxis for world wide use. Also apps to reach my non-native banks and things like that.
Finance: Specific profile for my crypto currencies, stock profiles and such on.
GF: In this profile my girlfriend has her applications, similar to what I do in Gulag. Protected by her code and finger print and so on - this way if she loses her phone while we are traveling or whatever, it's not as big of a problem anymore.
I share files between profiles using a NextCloud instance that I control the hardware to.
I use different email accounts for different things to in each profile only get the emails related to the tasks I perform in that specific profile.