klepto https://grapheneos.org/usage#banking-apps
Many of these apps have their own crude anti-tampering mechanisms trying to prevent inspecting or modifying the app in a weak attempt to hide their code and API from security researchers. GrapheneOS allows users to disable native code debugging via a toggle in Settings ➔ Security to improve the app sandbox and this can interfere with apps debugging their own code to add a barrier to analyzing the app. You should try enabling this again if you've disabled it and are encountering compatibility issues with these kinds of apps.
The section is about banking apps, since they're mostly the ones to employ such measures, but it doesn't just apply to banking apps. This is also the reason why native code debugging is enabled by default.