the0815 are there any safety implications?
I could go on for days about it.
The security model as well as the privacy features in GrapheneOS relies on the user not to open holes in the hardening. Adb, Shizuku, wireless or USB-debugging, and also device-admin, are exploitable opportunities for an attacker. And even running your daily device with enabled Developer options is highly unstable.
At least half of all serious issues that users brings to us, stems from their use of these things which also makes their issues very hard for us to diagnose and fix.