quit7327 Just for information the working config has the IP 192.168.178.213 and the broken one 192.168.168.204
178 vs 168? These are from two different subnets. Check the firewall rule on Fritz box re. the allowed WireGuard subnet. Maybe it allowed only for one IP (/32), not its whole subnet (/24).
I can confirm nothing wrong with GrapheneOS and/or WG client (official) or WG Tunnel app.
I have on my phone both, one set to connect to my router, one to a WG server inside my LAN (port forwarding) and both work as expected. Should be routing or firewall rule issue.