apache first of all welcome to the GOS community, everyone is super helpful.
Most (if not all) applications are compatible with GOS, you can optionally install Google Play Service and the Play Store (which benefit from being sandboxed) where most apps will be found but also Accresent App Store for a more privacy focused experience.
In relation to the work life and private life balance, as @n3t_admin noted there are multiple compliance standards and regulations across a multitude of countries that need to be considered (such as: GDPR, CCPA, NIS2, DORA, etc) as such probably best to keep things separate.
Below are some links for further reading that be help for both GOS (starting points) and IOS.
https://grapheneos.org/features
https://seprand.github.io/articles/best-user-profile-setup/
https://github.com/beerisgood/Mobile_Security