DeletedUser433 Enabling USB debugging starts the adbd process (ADB daemon) from the built-in shell user, but I guess you want it enabled only when logged in to a specific profile. Did you find out if this is possible?
Do note though, that as the ADB daemon is running as the shell user, it is not limited to that profile, and—as always—has very broad privileges. Like messing with all user's settings, packages, processes, accessibility services, files, adding users, removing users, reading logs, start logging, start background services, install packages, grant permissions etc.
So you might not be achieving what you think you're achieving by having it enabled "in" just one profile...
Also, I think I read you can only enable it from the Owner profile. Which makes sense considering the above.