GrouchyGrape I think there are several threads on the forum about Intune.
I believe that some administrator settings result in profile-installation failures, but I don't know whether there are settings combinations that are known to work. A large part of the problem is that Intune is often configured to expect that Google Play is automatically installed as a profile is created, because that is true on most systems that have Play, and also that Play has privileges that it doesn't have on GrapheneOS.
Aside from forum threads, there is an open issue: https://github.com/GrapheneOS/os-issue-tracker/issues/1821
Overall, in a sense it could be made to work, but at present I believe that would require a cooperative MDM administrator.