- Edited
There are no known exploits to the Titan M2 or the SecureElement.
That does not mean that one doesn't exist, just that if it does its existence hasn't been publicly revealed.
To the best of my knowledge, there are no known (or rumored) technical exploits for an up to date Pixel running GOS. Every compromise I have been able to find was a user fault and/or alternative methods being used to gain the PIN.
Again, if you get on the US governments fuck you list (where they will drone strike you or have Delta do a bit of extraordinary rendition) then all bets are off. Otherwise, up to date GOS on a supported Pixel used in line with best practices remains secure.